The Santillo Hotel is the infamous hotel and bar run by Leon Saijo. The hotel appeals to the more classy and civilised population of New London however Leon insists that everyone is welcome to drink there and rent out rooms. The Hotel has become a hotspot for ex Saijo Gang members.

The Hotel used to be Leon's own personal mansion given to him by his father however after London fell and was rebuilt he decided to repair and refurbish it as a hotel for the citizens of new london. The hotel is constantly resupplied by the Abato Brewery, Leon's personal brewery which is used to produce the various alcohol sold at the bar, and the La Franchi State farm, a nearby farm which supplies the hotel with food to feed its guests.